Posts Tagged ‘2006’

Red Hot Cool Groove

vrijdag, december 16th, 2011
TitleRed Hot Cool Groove
Screenshotlogosid
Year2006
Estimated date2006-07-06
CategoryMusic
PlatformNone
DescriptionDries and I jammed away (I did the drums, he the bass). And then he records all that other stuff on top of it. Great jam! A typical Dus project.
FileDownload

A genetic variant of the CC-chemokine CCL2 is associated with renal function decline in PREVEND

vrijdag, december 16th, 2011
TitleA genetic variant of the CC-chemokine CCL2 is associated with renal function decline in PREVEND
Screenshotlogodoc
Year2006
Estimated date2006-04-03
CategoryScientific presentation
PlatformNone
DescriptionA presentation about my research for my colleagues at the Department of Medical Biology.
FileDownload

GENECURE workpresentation November 2006

vrijdag, december 16th, 2011
TitleGENECURE workpresentation November 2006
Screenshotlogodoc
Year2006
Estimated date2006-11-08
CategoryScientific presentation
PlatformNone
DescriptionI was project manager of the GENECURE consortium. This is a presentation I held in Stockholm concerning our own research.
FileDownload

CC-Chemokine 5 receptor del32 polymorphism protects against the increased mortality rate seen in dialysis patients with systemic inflammation

donderdag, december 15th, 2011
TitleCC-Chemokine 5 receptor del32 polymorphism protects against the increased mortality rate seen in dialysis patients with systemic inflammation
Screenshotlogodoc
Year2006
Estimated date2006-10-10
CategoryScientific Publication
PlatformNone
DescriptionOur poster for the American Society of Nephrology conference in 2006.
FileDownload

FileCutter 1.0.1

dinsdag, december 13th, 2011
TitleFileCutter 1.0.1
Screenshotfilecutter
Year2006
Estimated date2006-02-26
CategorySoftware
PlatformPC
DescriptionAn updated version of my original FileCutter tool to cut parts (header/tail) of a large file for analysis to save upload space/time.
FileDownload

An Increased Coronary Risk Is Paradoxically Associated with Common Cholesteryl Ester Transfer Protein Gene Variations That Relate to Higher High-Density Lipoprotein Cholesterol: A Population-Based Study

woensdag, december 7th, 2011
TitleAn Increased Coronary Risk Is Paradoxically Associated with Common Cholesteryl Ester Transfer Protein Gene Variations That Relate to Higher High-Density Lipoprotein Cholesterol: A Population-Based Study
Screenshotlogodoc
Year2006
Estimated date2006-03-01
CategoryScientific Publication
PlatformNone
DescriptionBackground: Several cholesteryl ester transfer protein (CETP) polymorphisms affect high-density lipoprotein (HDL) cholesterol, but the impact of CETP gene variants on incident coronary disease in the general population is uncertain after correction for their effect on HDL cholesterol. Design: We determined relationships between the CETP 629C3A promoter (n  8141), the TaqIB (n  8289), and the I405V (n  8265) polymorphisms, serum lipids, C-reactive protein, and clinical factors with incident coronary heart disease (defined as death from or hospitalization for myocardial infarction, ischemic heart disease, or coronary intervention) during a median of 4.94 yr follow-up. Subjects: A predominantly Caucasian general population was studied. Results: HDL cholesterol was 0.08 mmol/liter higher in 629A carriers than in 629CC homozygotes (P  0.001). The unadjusted coronary hazard was 1.26 [95% confidence interval (CI), 0.95–1.68; P  0.11] in A carriers compared with CC homozygotes and increased to 1.46 (95% CI, 1.10–1.95; P  0.01) after adjustment for HDL cholesterol. This effect remained after additional adjustment for apolipoprotein A-I, triglycerides, C-reactive protein, age, and gender. Likewise, the HDL-cholesterol-adjusted hazard ratio was also higher in AA than in CC homozygotes (hazard ratio, 1.72; 95% CI, 1.22–2.42; P  0.01). Similar findings were obtained with the TaqIB polymorphism. The 405V allele was weakly associated with incident coronary heart disease after HDL cholesterol adjustment (P  0.09). Conclusions: A common CETP promoter polymorphism, which beneficially contributes to higher HDL cholesterol, is paradoxically associated with increased incidence of coronary disease in the general population. Thus, CETP gene variation may affect coronary risk apart from the level of HDL cholesterol. (J Clin Endocrinol Metab 91: 3382–3388, 2006)
FileDownload